口服蔗糖水對早產兒疼痛反應的效益
口服蔗糖水對早產兒疼痛反應的效益
徐少慧 吳淑貞* 李穎俐**
慈濟技術學院護理系講師
慈濟技術學院護理系助理教授*
財團法人奇美醫院護理部專員**
摘 要
本研究目的在比較口服蔗糖水、口服蒸餾水及未餵食任何東西對早產兒扎腳跟血之疼痛的反應。研究對象為方便取樣之7位早產兒，方法為雙盲之類實驗設計，每位早產兒皆接受三種介入措施，並於實驗過程中持續監測心跳、呼吸、血氧飽和度及其行為變化。結果顯示，三組在扎腳跟血後之平均心跳及呼吸皆上升，但口服蔗糖水組之脈搏及呼吸穩定回復至基準值的時間較其他二組快。未給組在扎腳跟後第7分鐘之平均呼吸及血氧飽和度分別有明顯的上升及下降。 此外，各組在扎針前、後及後續的行為反應，未給組的區別性較大，由全組皆在睡眠中轉變為6人清醒，其中3人哭泣，到最後仍有4位清醒者。口服蒸餾水組在扎針後續有1人哭泣。口服蔗糖水組始終未有個案出現哭泣行為，且較容易返回睡眠狀態。 然而，以多變量重複量數檢定其心跳、呼吸、血氧飽和度共同表現皆無統計上顯著差異。本結果雖未達統計上顯著意義，仍顯示口服蔗糖水有減少早產兒接受針扎採血時所造成疼痛反應的趨勢，未來應增加樣本數進一步探討。
關鍵詞：早產兒、扎腳跟、口服蔗糖水、疼痛反應
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Effectiveness of Oral Sucrose on Pain Responses in Preterm Infants
Shao-Hui Shu Shu-Chen Wu* Ying-Li Lee**
Lecturer,
Assistant professor, Tzu-Chi College of Technology*
Coordinator of nursing department,
Abstract
The objective of this study was to investigate the effect of oral sucrose on the pain or distress response in premature infants’ heart rates (HR), respiration rates (RR), oxygen saturation (SaO2), and behavioral responses after heel stick. The study used a convenience sampling, double-blind and semi-experimental design. Seven premature infants with gestational age between 31~34 weeks, bodyweight between 1206-1824 grams and post-natal age >24 hours but <28 days without severe illness were selected. Each subject was randomized to receive three intervention, 0.5ml 25% oral sucrose, oral placebo (0.5ml sterilized water) or none intervention, in different day.
The results showed (1)the variations of HR, RR and SaO2 among the three groups exhibited no significant differences; (2)difference in the measured variables before and after heel prick showed that time of returning to the baseline HR and RR was shorter in the sucrose group; (3)the none intervention group had crying response to heel stick; (4)the mean of none intervention group’s RR was sharply increased but SaO2 decreased after the 7th minute of heel prick; (5)the oral sucrose group was easy to return to sleep. Although the statistic analysis found there was no significant difference among three groups, the results of this study can serve as an illustration that oral sucrose in decreasing the suffering from stressful acute pain for premature infants. Future studies need explore the effects of oral sucrose on large sampling populations.
Keywords: premature, heel stick, oral sucrose, pain responses
